architectures invented in Eukaryota

red squares stand for ZnF_Gen
14_3_3
AAA AAA AAA AAA AAA AAA VWA
AAA AAA AAA AAA AAA VWA
AAA BROMO
ACTIN
ADEAMc
ADF
ADF ADF
ANK AAA
ANK BTB
ANK HECTc
ANK IQ IQ
ANK IQ IQ IQ
ANK RING
ANK SAM
ANK STYKc
ANK TPR TPR TPR
ANK ZnF_Gen
ANX
ANX ANX
ANX ANX ANX
ANX ANX ANX ANX
ARM
AT_hook AT_hook
AT_hook AT_hook AT_hook AT_hook AT_hook AT_hook AT_hook
AWS
AWS SET PostSET
ArfGap
B41
B41 ILWEQ
B561
BAH
BAH AAA
BAH BAH
BAR
BBOX
BBOX BBOX
BIR
BPI1 BPI2
BRCT AAA
BRCT BRCT
BRCT BRCT BRCT
BRCT BRCT BRCT BRCT
BRIGHT
BROMO
BSD
BSD BSD
BTB
BTB ANK
BTB BTB
BTB Kelch Kelch Kelch Kelch Kelch Kelch
BTP
C1
C1 C1
C1 C1 C1
C1 C1 DAGKc DAGKa
C2
C2 C2
C2 C2 C2
C2 C2 C2 C2
C2 C2 C2 C2 C2
C2 C2 PI3Ka PI3Kc
C2 C2 VWA
C2 PI3Ka PI3Kc
CARP
CARP CARP
CBF
CBS CBS CBS CBS PB1
CCP
CH
CH CH
CH CH CH
CH CH CH CH
CH CH SPEC EFh
CH IQ IQ IQ IQ
CHROMO
CHROMO CHROMO
CHROMO CHROMO DEXDc HELICc
CHROMO CHROMO DEXDc HELICc SANT
CHROMO ChSh
CHROMO DEXDc HELICc
CHROMO ZnF_Gen
CLH CLH CLH CLH CLH CLH CLH
CPDc
CPDc BRCT
CSP ZnF_C2HC ZnF_C2HC
CTLH
CTNS CTNS
CUE
CULLIN
CY CY
CY CY CY
CYCc CYCc
ChtBD1 ChtBD1
CysPc calpain_III
DAGKa
DAGKc DAGKa
DDT
DEP
DEXDc AAA HELICc SEC63 DEXDc AAA HELICc SEC63
DEXDc ANK HELICc
DEXDc HELICc BROMO
DEXDc HELICc RIBOc RIBOc
DEXDc HELICc RIBOc RIBOc DSRM
DEXDc HELICc SANT
DEXDc HELICc SANT SANT
DEXDc HELICc ZnF_C2HC
DEXDc RING
DEXDc RING HELICc
DEXDc2 HELICc2
DEXDc3
DSRM DSRM
DSRM DSRM DEXDc HELICc
DSRM DSRM DSRM
DUSP
DYNc
DYNc GED
DnaJ SANT SANT
DnaJ SEC63
DnaJ ZnF_Gen ZnF_Gen
DnaJ ZnF_Gen ZnF_Gen ZnF_Gen
DoH
DoH B561
DoH DoH B561
EFh CH CH CH CH
EGF_like FU EGF_like
EGF_like FU EGF_like FU EGF_like
EGF_like FU FU
EGF_like FU FU EGF_like FU EGF_like
EGF_like STYKc
EH
EH EFh
EH EFh EH EFh
ENTH
FBD
FBOX
FBOX ANK
FBOX ARM
FBOX FBOX
FBOX LRR LRR LRR
FBOX LRR LRR LRR LRR LRR LRR
FBOX LRR LRR LRR LRR LRR LRR LRR LRR
FBOX LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR
FBOX LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR
FBOX WD40
FCH SH3
FF FF FF
FH2
FHA BRCT BRCT
FOLN FOLN
FOLN FOLN FOLN
FOLN FOLN FOLN FOLN FOLN FOLN FOLN FOLN
FU
FU EGF_like
FU EGF_like FU EGF_like
FU EGF_like FU EGF_like FU EGF_like FU EGF_like FU EGF_like
FU EGF_like FU EGF_like FU EGF_like FU EGF_like FU EGF_like FU EGF_like FU EGF_like
FU FU
FU FU EGF_like FU EGF_like
FU FU EGF_like FU EGF_like FU EGF_like
FU FU EGF_like FU EGF_like FU EGF_like FU
FU FU FU
FU FU FU EGF_like FU FU
FU FU FU FU
FU FU FU FU FU FU EGF_like
FYRN FYRC
FYVE
FYVE PIPKc
GAF GAF HDc
GAL4 PAS
GEL GEL
GEL GEL GEL
GEL GEL GEL GEL GEL
GEL GEL GEL GEL GEL GEL
GEL GEL GEL GEL GEL GEL VHP
GEL GEL GEL GEL VHP
GIYc IENR2 IENR2 IENR1
GLECT
GRAM
GRAN
GYF
G_alpha
G_patch
G_patch KOW KOW
G_patch RRM
G_patch RRM_1
Grip
H15
H2A
H2B
H3 H3
H4
HAT HAT
HAT HAT HAT
HAT HAT HAT HAT
HAT HAT HAT HAT HAT
HAT HAT HAT HAT HAT HAT
HAT HAT HAT HAT HAT HAT HAT
HAT HAT HAT HAT HAT HAT HAT HAT
HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT
HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT
HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT
HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT
HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT
HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT HAT
HAT HAT HAT HAT HAT HAT HAT RRM
HATPase_c TOP2c TOP4c
HECTc
HELICc SANT SANT
HELICc SEC63
HLH
HLH HLH
HMG
HMG HMG
HSA
HSA DEXDc HELICc SANT
HSA SANT
HSF HSF
HX HX HX
HintC
IBR
IBR IBR
IBR RING IBR
IBR ZnF_C2HC IBR
IG_FLMN
IG_FLMN IG_FLMN IG_FLMN IG_FLMN IG_FLMN
IPPc RhoGAP
IQ HECTc
IQ IQ
IQ IQ IQ
IQ IQ IQ IQ
IQ IQ IQ IQ IQ
IQ PP2Ac EFh
JmjC PHD
JmjN BRIGHT PHD JmjC PHD
JmjN JmjC
KAZAL KAZAL KAZAL KAZAL
KH KH KH
KH KH KH KH
KH KH KH KH KH
KH ZnF_C2HC ZnF_C2HC
KISc
KISc HhH1
KISc PH
KOW KOW KOW KOW KOW
KR
Knot1
Ku78 SAP
LA
LA RRM
LA RRM RRM_2
LDLa
LH2
LIM
LIM LIM
LIM LIM LIM
LIM LIM LIM LIM
LIM LIM LIM LIM LIM
LITAF
LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR
LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR
LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRR LRRcap
LRR LRR LRR LRR LRR LRRcap
LRR LRR LRR LRR STYKc
LRR LRR LRR LRRcap
LRR LRR LRRcap
LRRcap
LYZ1
LisH AAA
LisH CTLH
LisH CTLH RING
LisH CTLH WD40
LisH WD40
LysM TLDc
MA3
MATH
MATH BTB
MATH MATH
MATH MATH MATH MATH
MBD
MIF4G
MIF4G MA3
MIF4G MIF4G
MIR MIR MIR
ML
MORN
MORN MORN MORN MORN MORN MORN MORN
MORN MORN MORN MORN MORN MORN MORN MORN
MORN MORN MORN MORN MORN MORN MORN MORN MORN
MYSc
MYSc IQ
MYSc IQ IQ
MYSc IQ IQ IQ
MYSc IQ IQ IQ IQ
MYSc IQ IQ IQ IQ IQ
MYSc IQ IQ IQ IQ IQ IQ
MYSc IQ IQ IQ IQ IQ IQ IQ
MYSc IQ IQ MyTH4 B41 SH3 MyTH4 B41
MYSc SH3
Mterf Mterf Mterf
Mterf Mterf Mterf Mterf
Mterf Mterf Mterf Mterf Mterf
Mterf Mterf Mterf Mterf Mterf Mterf
Mterf Mterf Mterf Mterf Mterf Mterf Mterf
MyTH4 B41
NGN KOW KOW KOW KOW KOW KOW
PA2c
PAM
PAM PINT
PAN_AP
PB1
PB1 ZnF_ZZ
PBD
PBD STYKc
PBPe
PDZ PDZ PDZ
PH
PH ArfGap ANK
PH FYVE
PH PBD STYKc
PH PH
PH PLDc PLDc
PH RhoGAP
PH START
PH STYKc
PH STYKc S_TK_X
PHD
PHD CHROMO CHROMO DEXDc HELICc
PHD PHD
PHD PHD PHD
PHD PHD PHD PHD
PHD PHD PHD RING
PHD PHD RING PHD RING
PHD RING
PHD RING CHROMO CHROMO DEXDc HELICc
PHD RING PHD
PHD RING PHD RING
PHD RING PHD RING PHD
PHD RING PHD RING PHD RING
PHD SET
PI3K_rbd C2 PI3Ka PI3Kc
PI3Ka PI3Kc
PI3Kc
PINT
PIPKc
PLCXc PLCYc
PLCXc PLCYc C2
PLCYc C2
POLXc
POLXc HhH1 HhH1
PQQ PQQ PUG
PROF
PSI
PSP
PUG
PUG UBX
PUR PUR PUR
PWI
PX
PX STYKc
PlsC EFh
Plus3
PolyA
PreSET SET PostSET
Pumilio Pumilio Pumilio
Pumilio Pumilio Pumilio Pumilio
Pumilio Pumilio Pumilio Pumilio Pumilio
Pumilio Pumilio Pumilio Pumilio Pumilio Pumilio
Pumilio Pumilio Pumilio Pumilio Pumilio Pumilio Pumilio
Pumilio Pumilio Pumilio Pumilio Pumilio Pumilio Pumilio Pumilio
R3H DEXDc HELICc
RGS
RHOD PTPc_DSPc
RIBOc RIBOc
RING ANK
RING BBOX
RING BRCT
RING BRCT BRCT
RING EGF_like
RING HELICc
RING IBR
RING IBR IBR
RING IBR IBR RING
RING IBR RING
RING IBR RING IBR
RING IBR ZnF_C2HC IBR RING
RING MATH
RING PHD
RING PHD PHD RING
RING RING
RING RING RING
RING RRM
RING WD40
RING ZnF_Gen
RING ZnF_Gen ZnF_Gen
RING ZnF_Gen ZnF_Gen ZnF_Gen
RING ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen
RING ZnF_NFX ZnF_NFX ZnF_NFX ZnF_NFX ZnF_NFX ZnF_NFX ZnF_NFX
RING ZnF_NFX ZnF_NFX ZnF_NFX ZnF_NFX ZnF_NFX ZnF_NFX ZnF_NFX ZnF_NFX ZnF_NFX
RING ZnF_UBP
RING ZnF_ZZ
RINGv
RPOL4c
RPOL8c
RPR
RRM PWI
RRM PolyA
RRM RING
RRM RRM_2
RRM RRM_2 RRM
RRM RRM_2 RRM_2
RRM SWAP RPR
RRM WW
RRM ZnF_C2HC
RRM ZnF_C2HC ZnF_C2HC
RRM ZnF_Gen
RRM ZnF_Gen ZnF_Gen
RRM ZnF_RBZ
RRM ZnF_RBZ ZnF_RBZ
RRM_2
RRM_2 RRM
RRM_2 RRM RRM_2
RRM_2 RRM_2
RWD
RWD RING
RWD RING IBR IBR RING
RWD STYKc
RanBD
RasGAP
RasGEF
RasGEFN RasGEF
RhoGAP
RhoGEF PH
RhoGEF PH FYVE
S1 DEXDc HELICc
S1 S1 S1 S1 S1 S1 S1 S1 S1 S1 S1 S1 S1 HAT HAT HAT HAT HAT HAT
SAM
SAM PH
SAM STYKc
SANT SANT SANT SANT
SANT SANT SANT SANT SANT
SANT SET
SAP PHD
SCP
SEC14
SEP UBX
SFM
SFM WD40
SH2
SH2 RING
SH3 RhoGAP
SH3 SH3 SH3
SNc SNc
SNc SNc SNc
SNc SNc SNc SNc TUDOR
SNc SNc TUDOR
SPRY
SR SR
START
STI1
STYKc ANK
STYKc EFh
STYKc PH
STYKc STYKc
STYKc S_TK_X
STYKc UBA
SWAP
SWAP G_patch
SWAP RPR
SWAP SWAP
SWAP SWAP UBQ
S_TK_X
SapB
SapB SapB
SapB SapB SapB
SapB SapB SapB SapB
Skp1
SynN
SynN t_SNARE
TBC
TBC RHOD
TECPR TECPR TECPR TECPR TECPR TECPR
TFS2M
TFS2N
TFS2N TFS2M ZnF_C2C2
THN
TLC
TLDc
TNFR
TOP2c TOP4c
TOPEUc
TPR TPR TPR PP2Ac
TPR TPR TPR STI1
TPR TPR TPR STI1 TPR TPR TPR TPR TPR STI1
TPR TPR TPR STI1 TPR TPR TPR TPR TPR TPR STI1
TPR TPR TPR TPR DnaJ
TPR TPR TPR TPR TPR DnaJ
TPR TPR TPR TPR TPR TPR DnaJ
TPR TPR TPR TPR TPR TPR TPR TPR DnaJ
TPR TPR TPR TPR TPR TPR TPR TPR TPR STI1
TPR TPR TPR Ubox
TR_FER
TSP1
TSP1 TSP1
TSP1 TSP1 TSP1
TSP1 TSP1 TSP1 TSP1
TSP1 TSP1 TSP1 TSP1 TSP1 TSP1
TUDOR
UAS UBX
UBA UBA
UBCc UBA
UBQ
UBQ BAG
UBQ CPDc
UBQ STI1 STI1
UBQ STI1 STI1 STI1 STI1 UBA
UBQ STI1 UBA
UBQ UBA
UBQ UBA STI1 UBA
UBQ UBA UBA
UBQ UBQ
UBQ UBQ UBQ
UBQ UBQ UBQ UBQ
UBQ UBQ UBQ UBQ UBQ
UBQ UBQ UBQ UBQ UBQ UBQ
UBQ UBQ UBQ UBQ UBQ UBQ UBQ
UBQ UBQ UBQ UBQ UBQ UBQ UBQ UBQ
UBQ UBQ UBQ UBQ UBQ UBQ UBQ UBQ UBQ UBQ
UBX
UIM
UIM UIM
UIM UIM UBX
UIM UIM UIM
Ubox
Ubox RING
Ubox WD40
VHS
VPS10
VPS9
VWA Ku78
VWA RING
VWA UIM UIM
VWA UIM UIM UIM
VWA ZnF_Gen
WAP
WD40 CLH
WD40 CLH RING
WD40 IPPc
WH2
WR1
WW
WW WW
WW WW FF FF
WW WW FF FF FF
WW WW FF FF FF FF
WW WW FF FF FF FF FF
XPGI HhH2
XPGN
YqgFc S1 SH2
ZnF_A20 ZnF_AN1
ZnF_AN1 ZnF_AN1
ZnF_C2HC CHROMO
ZnF_C2HC PSP
ZnF_C2HC RING
ZnF_C2HC RRM
ZnF_C2HC ZnF_C2HC
ZnF_C2HC ZnF_C2HC ZnF_C2HC
ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC
ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC
ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC
ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC
ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC ZnF_C2HC
ZnF_GATA
ZnF_GATA ZnF_GATA
ZnF_Gen ANK
ZnF_Gen AT_hook ZnF_Gen ZnF_Gen
ZnF_Gen G_patch
ZnF_Gen KOW
ZnF_Gen RING
ZnF_Gen RRM
ZnF_Gen RRM ZnF_Gen
ZnF_Gen RRM_1 ZnF_Gen
ZnF_Gen ZnF_Gen RING ZnF_Gen
ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen
ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen
ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_C2HC ZnF_C2HC
ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen
ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen
ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen
ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen ZnF_Gen
ZnF_PMZ
ZnF_RBZ ZnF_RBZ ZnF_RBZ
ZnF_RBZ ZnF_RBZ ZnF_RBZ ZnF_RBZ
ZnF_RBZ ZnF_RBZ ZnF_RBZ ZnF_RBZ ZnF_RBZ ZnF_RBZ
ZnF_Rad18
ZnF_TAZ
ZnF_TTF
ZnF_UBP
ZnF_UBP UBA
ZnF_UBP UBA UBA
ZnF_ZZ
ZnF_ZZ SANT
Zpr1 Zpr1
cNMP cNMP cNMP
eIF2B_5 eIF5C
eIF5C
smallGTPase
smallGTPase BTB BTB
smallGTPase smallGTPase
smallGTPase small_GTPase
small_GTPase smallGTPase
t_SNARE
t_SNARE t_SNARE